Abstract
In the field of hemodialysis (HD), purification and management methods have been investigated to improve prognosis and quality of life (QOL). Considering increase in dialysis dose based on internal filtration, we provide high flux treatment with a blood flow rate of at least 350 mL/min at our clinic. The impact of high-flux HD with as few daily restrictions as possible on vital prognosis, including QOL, was compared between our data and the Japanese Society for Dialysis Therapy and other research data. The efficiency of dialysis, dialysis dose, nutrition index, and QOL of high-flux HD tended to be high, and the crude death rate was sufficiently low at 5.2%, whereas the rate was high at 21.9% in long-term dialysis patients with more than a 20-year history of HD. If internal filtration increases with high blood flow, high dialysis dose can eliminate a great number of poor prognosis factors, and good nutritional status not requiring dietary restrictions can be maintained through high dialysis dose, contributing to the improvement of QOL. High-flux hemodialysis is an important basic condition to improve vital prognosis and QOL.
