Abstract
The patient was a 25-year-old male who was diagnosed with Alport syndrome at the age of 3. His renal function gradually decreased, and peritoneal dialysis was initiated at the age of 8. He received a living kidney transplantation at the age of 9. Unfortunately, his graft function gradually deteriorated because of chronic rejection. At the age of 19, he was diagnosed with hemophilia A due to repeated nasal hemorrhaging and his family history. His hemophilia A was mild, and his factor Ⅷ level was>10%. At the age of 21, a second round of renal replacement therapy was required. Hemodialysis without anticoagulation agents was only possible via the infusion of 500 units of factor Ⅷ at the end of the dialysis session. Dialysis treatment was successfully continued without severe hemorrhagic events or blood clotting within the dialysis circuit.