2018 Volume 51 Issue 1 Pages 99-102
Exercise during hemodialysis increased the efficacy of solute removal in some studies. The goal of this study was to compare the removal of solutes between hemodialysis patients that did and did not perform aerobic exercises and to establish an effective protocol for exercise therapy during hemodialysis. We recruited 4 male patients that were undergoing online predilution hemodiafiltration (blood flow rate: 250 mL/min, total dialysate flow rate: 650 mL/min, substitution flow rate: 40 L/session, a constant body fluid removal rate, and an ABH-21P hemofilter). In the exercise sessions, the patients pedaled on a cycle ergometer for 60 minutes. The intensity of the exercise was set at peak VO2 of 30, 40, 50, and 60%. The total and hourly dialysate and hourly blood samples were collected. The total amounts removed, clear spaces, and reduction rates of urea, potassium, phosphate, β2-microglobulin, and α1-microglobulin were calculated. Also, the levels of bone metabolic markers in the hourly blood samples were measured. The total clear space of phosphate was higher in the patients that performed low intensity exercise than in those that participated in moderate intensity exercise. Among all patients, the clear space of phosphate was slightly higher during the exercise hour than during the control hour. The exercise did not affect the removal of urea, potassium, β2-microglobulin, or α1-microglobulin or the levels of bone metabolic markers. These findings suggest that low intensity exercise could improve long-term phosphate control in hemodialysis patients.
