Investigation of neutralizing antibody titers after mRNA SARS‒CoV‒2 vaccination in dialysis patients

Abstract

Neutralizing antibody titers were measured in healthy subjects and hemodialysis patients after two doses of a new coronavirus vaccine. The antibody titers of the hemodialysis patients were significantly lower than those of the healthy subjects, and some hemodialysis patients were not antibody‒positive. We consider that dialysis patients produce weaker immune responses and that the vaccine may not be fully effective in some cases. We hope that the measurement of neutralizing antibody titers in dialysis patients after vaccination will lead to evaluations of the risk of infection among these patients.