A case of subacute renal injury with myxoedema coma treated with hemodialysis and successfully weaned from dialysis with thyroid hormone replacement

Abstract

The patient was a 90-year-old woman. She was brought to our hospital for close examination and treatment, including the introduction of dialysis. Renal dysfunction that had worsened from Cre：1.97 to 3.86 mg/dL over a period of 1 year, respiratory distress, and pleural effusion were also observed. After hospitalization and close examination, myxoedema coma was diagnosed, and thyroid hormone replacement was performed along with continuous hemodiafiltration (CHDF). The renal function showed improvement and the patient was transferred to hemodialysis (HD), and could be subsequently weaned off HD. Hypothyroidism is an infrequent cause of renal dysfunction, but prompt intervention has been shown to improve the renal function. When searching for the cause of renal dysfunction, as in the present case, hypothyroidism should be considered, and close examination, including measurement of hormone levels, should be performed.