2023 Volume 56 Issue 8 Pages 317-322
Uremic pericarditis in patients with impaired kidney function is relatively rare. In this report, we describe two cases of cardiac tamponade in men who underwent dialysis reinitiation after kidney transplantation. Case 1 was a 41-year-old man who underwent peritoneal dialysis at 31 years old due to IgA nephropathy, followed by living donor kidney transplantation 7 months later. Three months after reinitiation, chest pain and hypotension led to a diagnosis of cardiac tamponade, and pericardial drainage was performed. Case 2 was a 48-year-old male who started hemodialysis at 25 years old due to IgA nephropathy and underwent cadaveric kidney transplantation at 34 years old. On the 10th day after dialysis reinitiation, he developed hypotension and dyspnea during dialysis, and pericardial drainage was performed with a diagnosis of cardiac tamponade. Thereafter, dialysis was continued with nafamostat mesilate, and aspirin and colchicine were started. Both patients were discharged from the hospital without recurrence. Drug therapy may be effective in preventing uremic pericarditis recurrence in dialysis patients with severe pericarditis who present with cardiac tamponade.