Toe‒brachial Pressure Index as Prognostic Indicator of Major Cardiovascular Events in Maintenance Hemodialysis Patients

Abstract

Objective： To examine the efficacy of using the toe‒brachial pressure index (TBI) as a prognostic indicator of major adverse cardiovascular events (MACE) in patients undergoing maintenance hemodialysis (HD). Methods： Prognostic factor analysis was conducted in 157 HD patients, involving the evaluation of various parameters including the ankle‒brachial pressure index (ABI), TBI, and skin perfusion pressure (SPP), in relation to the occurrence of MACE. Results： Cox proportional hazards model analysis revealed TBI to be the most significant independent prognostic factor (p ＜0.001). In receiver operating characteristic (ROC) curve analysis for MACE prediction, TBI demonstrated superior predictive capability with an area under the curve of 0.79 and optimal cut‒off value of 0.56. Conclusion： TBI is an effective prognostic indicator of MACE in hemodialysis patients.