2026 Volume 59 Issue 4 Pages 292-299
Non‒occlusive mesenteric ischemia (NOMI) is a disease associated with a poor prognosis involving intestinal ischemia, despite the absence of organic obstruction within mesenteric vessels. It has been reported that being a hemodialysis (HD) patient is both a risk factor for NOMI onset and poor prognostic factor. However, it remains unclear how HD patients with NOMI differ from non‒HD patients in terms of perioperative characteristics. In this study, we compared 12 HD and 31 non‒HD patients who underwent surgery for NOMI at our hospital. Despite there being no difference in the time from NOMI onset to surgery, 30‒day mortality was significantly higher in HD patients. Compared with non‒HD patients, HD patients exhibited the following characteristics：① no elevation of lactate or CK levels at NOMI diagnosis, ② shorter affected bowel length, and ③ papaverine administration potentially contributes to an improved prognosis. We concluded that active papaverine administration should be pursued and further case accumulation is necessary.
