Abstract
Abnormal metabolism of carbohydrate in chronic renal faliure is one of the most important problems on clinical practice, for the investigation of the lesion will develop the prognosis of dialysis patients. Abnormal metabolism of carbohydrate in chronic renal failure is called uremic psedodiabetes and is analogous to the behavior of chemical diabetes. This lesion is generally improved by dialysis.
On the other hand, insulin level in chronic renal failure is raised but we didn't find always a certain result on insulin response to glucose. Glucagon level is raised and besides glucagon response activity to protein meal. Regarding to growth hormone, its level is raised by renal failure because of deteroration of dissolution and abnormal secretory of itself. The behavior of C-peptide by loading arginine is not the same to that of insulin, which may be thought to be related to difference of hormone clearance in kidney. Hemoglobin A1 is increased by chronic renal failure, which cannot be said by abnormal metabolism of carbohydrte of renal failure, but is mainly due to the lesion of renal failure such as acidosis.
