Abstract
Sixteen cases with an initial diagnosis of hypoplastic or small kidney detected by IVP, VCG, Echogram, RI scan, CT scan or Angiography were studied. We investigated to find out what common factors affect their growth, the rate of change of creatinine concentration, and to find out possible effects of medical therapy.
Height and weight were graphed, which were well correlated with linear regression of the serum creatinine versus time. Analysis of these relation gave an estimation of progression of disease, the possible effects of therapy and to predict when dialysis will become necessary. The commonest reason for discovery were firstly due to episodes of urinary tract infection and secondary by routine school check ups for urinalysis (5/16) Of the 16 patients that were found to have a small kidney, 10 was finally diagnosed to have hypolastic kidney, 5 were bilateral, 5 were unilateral. Of the-patients that were found to have an atrophic kidney secondary to pyelonephritis, 3 of them were associated with bilateral VUR, one was associated with unileteral VUR. Impairment of renal function was observed in those who have bilateral renal anomaly with VUR, or who have unilateral UPJ obstruction and agenesis of another kidney.
The important roles of the pediatrician in prevention of chronic renal failure among those children are early recognition of the urinary tract infections which damage the renal function in them. Screening of proteinuria, hematuria and hypertension in asymptomatic children with renal anomaly is also useful in early detection in them, and is essential for the prevention of the development of chronic renal failure.
