Abstract
Amount of small solute removal (M) is measured not only by actual survey, but by collecting a part of whole drainage (dialysate or filtrate). In haemofiltration (HF) therapy, we proposed two different methods of measuring ‘M’ except actual survey (storing whole drainage). Because these methods gave quite close value each other, they are capable enough to apply in vivo.
In haemodialysis (HD) or haemodiafiltration therapy, it is actual survey which is in fact the only method to adapt, but it is impossible to measure ‘M’ with no considerable errors. So the simple method, which is proposed in this paper (only net fluid removal volume and its solute concentration are needed, using ultrafiltration controller), can be useful to know ‘M’ less than ±7% errors.
Then ‘M’ is proved to be in proportion to serum solute concentration before the therapy (C(0)) in each treatment method. So we proposed new index M/C(0) in order to compare the essential difference of small solute removal capacity between HD and HF. We concluded that HD therapy is more valuable than HF to remove larger amount of small solute, because it is theoretically and experimentally confirmed that ‘M’ is mainly dependent upon artificial kidney clearance.
Amount of removed solute is easily measured, using our methods, and they made it simple to evaluate solute removal performance in blood purification therapy.
