慢性腎不全患者の透析期間別にみた細胞性免疫能

大園 恵幸; 村谷 良昭; 川冨 正弘; 平井 義修; 原田 孝司; 原 耕平; 田浦 幸一; 松尾 新一郎; 広瀬 健; 松隈 玄一郎; 船越 衛一

doi:10.4009/jsdt1985.21.1027

Cell-mediated immunity in chronic hemodialysis patients in relation to the period of dialysis

Yoshiyuki Ozono, Yoshiaki Muraya, Masahiro Kawatomi, Yoshinobu Hirai, Takashi Harada, Kohei Hara, Koichi Taura, Shinichiro Mastuo, Takeshi Hirose, Genichiro Mastukuma, Morikazu Funakoshi

Author information

Yoshiyuki Ozono
Second Department of Internal Medicine, Nagasaki University
Yoshiaki Muraya
Second Department of Internal Medicine, Nagasaki University
Masahiro Kawatomi
Second Department of Internal Medicine, Nagasaki University
Yoshinobu Hirai
Second Department of Internal Medicine, Nagasaki University
Takashi Harada
Second Department of Internal Medicine, Nagasaki University
Kohei Hara
Second Department of Internal Medicine, Nagasaki University
Koichi Taura
Second Department of Internal Medicine, Nagasaki University
Shinichiro Mastuo
Nagasaki Municipal Adult Disease Center
Takeshi Hirose
Sakuramati Clinic
Genichiro Mastukuma
Sakuramati Clinic
Morikazu Funakoshi
Sakuramati Clinic

Keywords: chronic hemodialysis patients, cell mediated immunity, T cell subset, T cell function, tuberculosis

JOURNAL FREE ACCESS

1988 Volume 21 Issue 11 Pages 1027-1031

DOI https://doi.org/10.4009/jsdt1985.21.1027

Details

Abstract

We investigated cell-mediated immunity in dialysis patients. The data indicated that dialysis patients have lymphopenia, decreased reaction of PPD and decreased blastoid formation of PHA.
PPD reaction and T-cell function decreased in the early stage of dialysis and improved in the stage of maintenance dialysis, then subsequently decreased again in the long-term stage of dialysis.
These data suggests that patiens on dialysis have decreased immunologic host defense in the early and long-term stages of dialysis.

Corresponding author

Register with J-STAGE for free!