Abstract
The standard body weight (SW) in hemodialysis (HD) patients has been generally calculated using blood pressure, cardio-thoracic ratio (CTR), and so on. However, it is difficult to estimate SW with this method in some HD patients. We measured total body water (TBW) by administration of 99.8% deuterium oxide and calculated the lean body mass (LBM) from the height, body weight (BW), and waist girth. Body fluid volume and SW were estimated from TBW and LBM in HD patients and the results compared with those in normal subjects. In HD patients, TBW/BW was greater than in normal subjects by 3-4% in males and 5-10% in females, respectively. No relationships among CTR, SW and TBW were observed. A TBW/LBM value of >0.78 was suggested to indicate an overhydrated state in HD patients, and the mean TBW/LBM in such patients was 0.757, which was greater than that in normal subjects. Hypotensiòn during HD was induced by excess ultrafitration, regardless of the value of TBW/LBM.
