Abstract
We report the results of a trial of the analgesic effects of aqueous gel containing 10% lidocaine with 3% glycyrrhetinic acid mono 3-0 hemiphatalate sodium as an absorption promotor to relieve the pain of venepuncture in hemodialysis patients. A square sponge (20mm in length and 1mm in thickness) filled with approximately 0.3g of gel was applied to the surface of the forearm and kept covered with an adhesive plastic film (Tegaderm®) for 60min, which was the time it took for the maximum analgesic effect to be attained, sixty min application of the gel produced a painscore under “slightly painful” 94 times in 11 cases (original disease; CGN). During the trial, no signs or symptoms were observed in the skin and A-V fistula under the covering. These results suggest that this gel can provide effective local anesthesia for venepuncture in chronic hemodialysis patients.
