Abstract
We examined serum cardiac myosin light chain 1 [MLCI], serum creatine kinase [CK], lactate dehydrogenase [LDH], and serum myoglobin levels in 10 patients with heart disease, and in 12 patients without heart disease on maintenance hemodialysis [HD] before and after HD.
The MLCI level of HD patients was not decreased after HD, suggesting that MLCI was not dialyzed. Furthermore, there was no significant difference in MLCI level between patients with and without heart disease. The MLCI level was positively correlated with myoglobin level in every HD patient.
These data suggest that in HD patients the MLCI level is not useful in assessing cardiac involvement or damage due to HD, since MLCI in these patients may reflect skeletal muscle myosin light chain.
