Abstract
A 54-year-old female patient with Wegener's granulomatosis who had received maintenance hemodialysis for 8 years is reported. Hemodialysis was started due to rapidly progressive glomerulonephritis and glucocorticoid treatment was initiated because of polyarthralia and a high titer of rheumatoid factor. She suffered from nasal sinusitis 6 years later, and was admitted to our hospital 8 years later because of severe skin rash affecting the extremities with blisters and ulcers. She had never experienced pulmonary complications. Biopsy findings of the kidney, sinus mucosa and skin were compatible with Wegener's granulomatosis. C-ANCA was 88U on admission and decreased to 24U after remission was achieved with corticosteroids. C-ANCA is a useful tool for diagosing and evaluating the therapy for Wegener's granulomatosis.
