Abstract
Gastrointestinal endoscopic findings of 104 dialysis patients (90 on hemodialysis, 14 on CAPD) were checked against those obtained by mass health screenings (6, 623 cases). Of the patients on dialysis, 21.5% suffered from oozing of the gastric mucosa. We speculate that oozing of the gastric mucosa is a gastric lesion specific to dialysis patients. In a comparison of 22 hemodialysis patients with normal endoscopic findings with 20 hemodialysis patients with oozing of the gastric mucosa, for risk factors, there were no differences between the two groups in terms of age, dialysis period, predialysis calcium level, β2 microglobulin level, KT/V or the atherosclerotic index. However, steroid and nonsteroidal anti-inflammatory drugs had been administered in greater dosages to the oozing group than to the normal group. We suggest that the inhibition of prostaglandin is related to the pathogenesis of oozing of the gastric mucosa.
