Abstract
APLS with coagulation abnormalities due to antiphospholipid antibody detectable in the form of anti-cardiolipin is characterized by thrombosis, habitual abortion and neurological abnormalities, as well as renal disease terminating in end-stage renal failure. Here, we report a patient with APLS with a past history of multiple vascular accidents, including pulmonary infarction, cerebral thrombosis and bleeding, and thrombophlebitis, who ultimately developed terminal renal failure requiring dialysis therapy. Although he was initially treated with thrice-weekly hemodialysis, it subsequently became impossible to maintain it because of recurrent episodes of arteriovenous fistula occlusion, and he had to be switched to CAPD therapy. CAPD proved to be quite satisfactory and the patient's subsequent clinical course has been stable and complication-free for almost two years. CAPD may be a treatment modality of choice for APLS patients with end-stage renal failure.