Abstract
Four chronic renal failure patients whose serum intact-PTH levels decreased considerably after intravenous administration of saccharated iron to treatment iron deficiency are described. The patients had been undergoing maintenance hemodialysis therapy for 4 to 9 years, and their serum intact-PTH levels had increased to 145-1, 050pg/ml with a concomitant increase in alkaline phosphatase activity and Pi levels in 2 of the 4 cases, suggesting the presence of secondary hyperparathyroidism. The intact-PTH levels diminished to 57% to 10% of the initial levels after administration of iron, but increased again in every cases after discontinuing iron therapy. Indications for the clinical use of iron should be further examined to determine whether it can serve as a supplementary treatment procedure for secondary hyperparathyroidism.
