A case of chronic renal failure complicated by adrenocortical carcinoma

Aiji Yajima; Takayoshi Yanagisawa; Harushige Nozaki; Ikuo Takayashi; Tsunamasa Inou; Yumi Terasaki; Kimiko Ohtsubo; Hisayuki Sugimoto; Osamu Ohtsubo; Nobuyuki Hiruta; Kioko Kawai; Hideki Yoshida; Takashi Tominaga; Youji Nishimura

doi:10.4009/jsdt.29.1165

Aiji Yajima, Takayoshi Yanagisawa, Harushige Nozaki, Ikuo Takayashi, Tsunamasa Inou, Yumi Terasaki, Kimiko Ohtsubo, Hisayuki Sugimoto, Osamu Ohtsubo, Nobuyuki Hiruta, Kioko Kawai, Hideki Yoshida, Takashi Tominaga, Youji Nishimura

Author information

Aiji Yajima
Department of Urology, Towa Hospital
Takayoshi Yanagisawa
Department of Surgery, Towa Hospital
Harushige Nozaki
Department of Surgery, Towa Hospital
Ikuo Takayashi
Department of Surgery, Towa Hospital
Tsunamasa Inou
Department of Surgery, Towa Hospital
Yumi Terasaki
Department of Internal Medicine, Sangenjaya Hospital
Kimiko Ohtsubo
Department of Internal Medicine, Sangenjaya Hospital
Hisayuki Sugimoto
Department of Surgery, Sangenjaya Hospital
Osamu Ohtsubo
Department of Surgery, Sangenjaya Hospital
Nobuyuki Hiruta
Department of Pathology, Toho University
Kioko Kawai
Department of Pathology, Nagasaki University
Hideki Yoshida
Department of Urology, Showa University
Takashi Tominaga
Department of Urology, Mitsui Memorial Hospital
Youji Nishimura
Department of Urology, Mitsui Memorial Hospital

JOURNAL FREE ACCESS

1996 Volume 29 Issue 7 Pages 1165-1169

DOI https://doi.org/10.4009/jsdt.29.1165

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Abstract

We report a case of chronic renal failure complicated by adrenocortical carcinoma. A tumor in the upper part of the left kidney was incidentally discovered by abominal CT scanning in a patient who had been undergoing chronic hemodialysis for 21 years.
Left total nephrectomy was performed. The tumor was 8×7×4.5cm in diameter and was proved to be of adrenocortical origin by positive staining for 3β-hydroxysteroid dehydrogenase. Further pathological findings satisfied 5 out of 9 items in the criteria described by Weiss and showed positive Vimentin staining, leading to the diagnosis of adrenocortical carcinoma. The patient died of sepsis unrelated to adrenalectomy 2 months postoperatively.
Adrenocortical carcinoma in a patient on chronic hemodialysis is very rare in Japan.

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