Pulmonary cryptococcosis in a patient with end-stage renal failure undergoing chronic hemodialysis treatment

Abstract

We report a case of pulmonary cryptococcosis occurring in a patient with end-stage renal failure undergoing chronic hemodialysis and oral corticosteroid treatments. A-74-year-old woman was admitted to our hospital with multiple nodular shadows in the lower lobe of the right lung on a chest roentgenogram. Cryptococci were isolated from bronchoalveolar lavage fluid and the serum was positive for cryptococcal antigen.
Therapy with 200mg of intravenous fluconazole every day for one week and three times per week for three months resulted in almost complete resolution of the lesions and disappearance of the cryptococcal antigen. No side effects were observed during administration of this drug.