Abstract
A 19-year-old man who had had right flank pain for 1 month underwent CT scanning, and bilateral non-enhanced renal masses 8.5×6.0cm and 5.0×3.0cm were revealed. He was admitted to our hospital complaining of nausea, and hemodialysis was started because of acute renal failure. Examination of a US-guided percutaneous biopsy specimen of the right renal tumor fielded a histological diagnosis of B-cell non-Hodgkin's lymphoma. No lesions other than the bilateral renal masses were found and he was diagnosed as having primary bilateral renal lymphoma (PRL). Marked diuresis was noted 24 hours after starting chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisolone. Hemodialysis was discontinued after 72 hours. After 6 courses of chemotherapy, complete remission was achieved with no detectable mass on the CT scan and renal function recoverd completely. PRL rarely occurs because lymphatic tissue is not present in the kidney. Reported cases of bilateral PRL are often associated with acute renal failure and the patients usually survive for less than 1 year. We report a case of bilateral PRL with acute renal failure in which complete recovery was achieved with chemotherapy.
