Follow-up of peritoneal net fluid absorption rate (PNFAR) using dextran 70 in children on peritoneal dialysis

Abstract

We examined the peritoneal net fluid absorption rate (PNFAR) using dextran 70 in 12 children, 8 boys and 4 girls, on peritoneal dialysis. Their average age was 12.5 years (6-17 yr). PNFAR measured using dextran 70 as a marker substance was 2.4ml-7.8ml/kg/4 hours (average 4.9±1.9ml/kg/4 hours). PNFAR measured 1 year later by the same method was 0.9-27.4ml/kg/4 hours (average 7.2±5.9ml/kg/4 hours). There was no correlation and no significant difference between the 2 PNFAR measurements in 12 patients (p=0.20), but a close correlation was observed in 6 patients (r=0.90, p=0.03), who had no residual renal function. We concluded that PNFAR follow-up should be performed separately in patients with residual renal function and in those with no residual renal function.