Abstract
We report our experiences in treating prostate cancer in hemodialysis patients.
Materials and Methods; From February 1999 to July 2000, we treated prostate cancer patients who underwent maintenance hemodialysis therapy in our hospital and related institutes.
Results; We encountered 5 cases of prostate cancer during a one and a half-year period. The patients were 65 to 86 years of age, and the mean duration of hemodialysis was 46.8 months (range; 13 to 71). The diseases underlying chronic renal failure were 3 cases of chronic glomerulonephritis, 1 case of polycystic kidney and 1 case of diabetic nephropathy. All cases underwent complete androgen blocking (CAB) therapy and we obtained a satisfactory response in all but one case. The measurement of serum PSA was useful for early diagnosis and follow-up of the clinical course.
Conclusions; In hemodialysis patients, serum PSA measurement was useful for early diagnosis and follow-up of prostate cancer as in patients with normal renal function. We could achieve good short-term results with CAB therapy, however further investigation of the long-term effectiveness of medical therapy is necessary.
