Abstract
Quadrivalent influenza vaccines were newly available and distributed in Japan from the 2015–16 influenza season. Adverse drug reactions to influenza vaccines among adults are rarely reported, so we carried out a questionnaire survey of adverse drug reaction following quadrivalent influenza vaccination coverage of our medical university and university hospital workers. Overall, 75.3% of adverse drug reactions, mainly solicited injection-site symptoms such as redness, swelling and pain, etc. were reported. No severe adverse drug reactions were reported. The type and frequency of adverse drug reaction were similar to previous reports, and quadrivalent influenza vaccination was well tolerated in adults.