Japanese Journal of Infection Prevention and Control
Online ISSN : 1883-2407
Print ISSN : 1882-532X
ISSN-L : 1882-532X
Short Paper
Clinical Characteristics of Substrate Specific Extended-spectrum β-lactamase Producing Escherichia coli Detected in the Urine Culture of Children
Naoyoshi MORIKei TAKABAYumi KAKIUCHIIssei TOKIMATSU
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JOURNAL FREE ACCESS

2017 Volume 32 Issue 1 Pages 13-17

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Abstract

The frequency of urinary tract infections (UTIs) is higher in children than in adults. Reportedly, Escherichia coli is suspected as the main phlogogenic microbe in UTIs. The substrate specific extended-spectrum β-lactamase (ESBL) producing E. coli has been frequently detected; therefore, selecting the initial treatment has become important. Here, we evaluated the clinical background and checked urine cultures of children for ESBL producing E. coli. Of the 88 E. coli specimens detected in these urine cultures, 12 were ESBL producing E. coli (13.6%). For patients who were diagnosed with recurrent UTI, had a history of medical intervention, or confirmed fluoroquinolone (broad-spectrum antibacterial drug) resistance, the rate of ESBL producing E. coli was significantly higher than for other cases. Therefore, if you happen to encounter a child patient with UTI, it is important to obtain a thorough clinical history of patients with UTIs, including previous medical intervention, considering that ESBL producing E. coli is resistant to fluoroquinolones.

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© 2017 Japanese Society for Infection Prevention and Control
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