Japanese Journal of Infection Prevention and Control
Online ISSN : 1883-2407
Print ISSN : 1882-532X
ISSN-L : 1882-532X
Review Article
Pharmacokinetics of Antimicrobial Chemotherapy Based on Maturation in Children
Yasuhiro TSUJI
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2021 Volume 36 Issue 2 Pages 77-82

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Abstract

Numerically, the most significant difference between children and adults is body weight. Humans are not born with complete physiological functions, and our body functions mature with growth. Assuming adult renal function to be 100%, glomerular filtration rate only reaches approximately 25%-40% of adult function at birth. Renal function reaches approximately 90% of adult function in the first year after birth and is comparable to adult function in the second year after birth. This review will discuss energy metabolism of living organisms, maturation from children to adults, pharmacokinetics in children, and describes antimicrobial chemotherapy in children.

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© 2021 Japanese Society for Infection Prevention and Control
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