2024 Volume 39 Issue 4 Pages 133-139
COVID-19 is the most common causative virus of nosocomial clusters. It is important for healthcare workers to prevent the introduction of the virus into hospitals. At Hospital A, the staff themselves focused on preventing infection in the home. Individual guidance was provided to staff members who had family members living with COVID-19. So far, there have been reports of household and secondary infection rates as a breakdown of positive cases; however, there have been no reports of factors that prevented infection. Therefore, this study aimed to investigate the factors that can lead to household transmission from family members living together to healthcare workers. A case control study was conducted on staff members who were infected during the infectious period (13 people) and those who were not (38 people). As a result of univariate analysis using the statistical software EZR statistical analysis, the age of the infected staff group was significantly lower than that of the noninfected staff group (median 39.7 years and 48.5 years, respectively). As a risk factor for household infection, it was found that the risk increases if the first infected person is under 6 years old, especially under 3 years old (odds ratio, 16.9; P value 0.002). The risk of infection was significantly lower if the previous infection was 18 years of age or older (odds ratio, 0.19; P value 0.005). Logistic regression analysis showed that the risk of infection was higher when there were two or more prior infections (odds ratio, 63.2; P value 0.0017). In addition, the implementation of individual guidance on infection control measures at home reduced the risk of infection (odds ratio, 50.9; P value 0.04).