2012 Volume 71 Issue 4 Pages 242-246
Fabry disease is an X-linked recessive disorder involving progressive lysosomal deposition of globotriaosylceramide (GL-3) in cells caused by a deficient activity of the enzyme α-galactosidase A (α-Gal A). Hearing loss, tinnitus, and dizziness are common symptoms in Fabry disease. We present herein on a case of Fabry disease in a 56-year-old man with bilateral hearing loss, tinnitus, and dizziness during walking. Rehabilitation therapy for adaptation of the vestibulo-ocular system was performed for dizziness during walking. The patient was examined by questioning, use of the visual analogue scale (VAS), and computerized dynamic posturography (Equitest). After 4 months of rehabilitation, VAS score and Equitest results improved. Rehabilitation therapy for adaptation of the vestibulo-ocular system may be effective for Fabry disease dizziness.
