Abstract
Three patients with Meniere's disease were treated with Aplactan, Contomin, Isobide and Triomin immediately at the onset of premonitory symptoms, such as tinnitus, hearing loss, sense of fullness of the affected ear. To differentiate between therapeutic effects and spontaneous improvement these drugs were prescribed many times for each patient.
Case 1, a 74-year-old male, was given Contomin, Aplactan and Triomin 10 times for 11 premonitory conditions from Nov. 1987 to May 1988. The attack was aborted 4 times.
Case 2, a 58-year-old female, was treated with Aplactan 7 times for 13 premonitory conditions from Mar. 1988 to May 1988. Vertigo was aborted 5 times.
Case 3, a 45-year-old male, was given Isobide, Triomin, Aplactan and Cercine 2 times for 9 premonitory conditions from Jan. 1988 to Apr. 1988. Vertigo was aborted once.
These results indicate that drug therapy in the premonitory stage of an attack can prevent attacks of vertigo in Meniere's desease.
