Abstract
Marbled flounder Pleuronectes yokohamaewere fed with a formulated diet spiked with
7 nitrated polycyclic aromatic hydrocarbons（NPAHs）during a 7-day intake period after which they were fed with NPAHs-free diet during the next 7 days as elimination period. Results showed that NPAHs concentrations in fish body were increased but levels were lower than in the dietary concentrations and did not show signs of accumulation. Genotoxicity was manifested in the significantly higher frequencies of micronuclei（MN） and other nuclear abnormalities（NA）formation in erythrocytes with higher frequencies of ΣMN+NA at day 7 in lower and higher dietary exposure groups at 42.3 and 45.7 per 1000 erythrocytes, respectively and 5.66 per 1000 erythrocytes in the control.
