Antibacterial Effect of Chemical Reagents against Tenacibaculum maritimum

Abstract

Minimum inhibitory concentrations (MICs) of 12 chemical reagents were determined for four strains of Tenacibaculum maritimum. Bronopol and stabilized chlorine dioxide showed the lowest MIC (1.0 μg/mL). With 6-h treatment, minimum bactericidal concentrations (MBCs) of bronopol and stabilized chlorine dioxide were 4.0 and ≤8.0 μg/mL, respectively. Both chemicals were non-toxic to five marine fishes in 6-h exposure at concentrations 5 times higher than the MBCs. The two chemicals are the most suitable candidates for antibacterial agents for treatment of T. maritimum infection.