Abstract
Studies were made on tissue levels of chloramphenicol (CP) in cultured eel, Anguilla japonicawhich were given 50 and 100 mg of CP per kilogram of body weight. The fish were fed the drugcontaining artificial food once a day for successive 5 days prior to the drug analysis. The water temperature was 23.8 to 25.4°C, average 24.7°C, during the course of experiment.
The highest tissue levels of CP were obtained 6 hours after last medication. The highest levels of CP were found in the kidney and the lowest levels were in the liver. The levels of CP in those tissues became almost undetectable after 48 hours.
Total nitro compound levels in tissues were also analyzed (Table 1 and 2).
