Abstract
Orally administered fumagillin DCH failed to protect rainbow trout (Oncorhynchus mykiss) from natural or experimentally-induced ceratomyxosis. No differences in mortality were observed between groups of trout exposed to Ceratomyxa shasta and fed fumagillin at 0.25 or 0.50 g/kg of diet at 2.0% fish body weight per day. Treatments with the drug however, did extend the mean time to death of trout due to C. shasta when compared to exposed but unmedicated controls. Extended feeding of the drug resulted in mortality in both infected and uninfected control groups. Malachite green was also ineffective in controlling ceratomyxosis when applied at 7 days intervals at 1.6 ppm for 40 min over a 64 day period.
