Quality Control Ranges of Minimum Inhibitory Concentrations for Lactococcus garvieae and Photobacterium damselae subsp .piscicida

Abstract

It is necessary to determine the quality control ranges of the minimum inhibitory concentrations (MICs) for fish pathogenic bacterial strains in order to achieve comparability of test results. We derived tentative quality control ranges for Lactococcus garvieae and Photobacterium damselae subsp. piscicida (2 strains each), by using the standard agar dilution method of the National Committee for Clinical Laboratory Standards. We measured the MICs of 14 drugs for the 4 strains and 5 quality control strains under culture conditions recommended for both aquatic bacteria and determined tentative quality control ranges from the modal MIC±1 log₂ dilution step.