Abstract
This report presents a case of Peutz- Jeghers syndrome (PJS) with a large (3 cm) polyp in the ascending colon that was detected by 18F-deoxyglucose positron emission tomography (FDG-PE'r) . Periodic gastrointestinal examination is a considerable stress for patients with PJS because polyps are distributed from the stomach to the rectum. It was revealed for the first time that a large hamartoma of PJS, which is not a cancer, could be detected by FOGPET. FDG-PET may be a useful tool for detecting large benign polyps associated with PJS.