JOURNAL OF FAMILIAL TUMORS
Online ISSN : 2189-6674
Print ISSN : 1346-1052
HNPCC and Endometrial Cancer
Kouji BannoNobuyuki SusumuTakeshi HiraoTakashi IwataAkira HirasawaDaisuke AokiShiro Nozawa
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JOURNALS OPEN ACCESS

2003 Volume 3 Issue 2 Pages 62-67

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Abstract

Hereditary nonpolyposis colorectal cancer(HNPCC) is a familial cancer of the autosomal dominant inheritance form. Since complications of endometrial cancers develop at a high frequency in HNPCC patients, it has become known that part of endometrial cancers are HNPCC-related familial cancers. It has also been suggested that ovarian cancers and breast cancers, in addition to endometrial cancers, are related to HNPCC. HNPCC-associated endometrial cancers appear to have unique characteristics biologically and clinico- pathologically, but the exact nature is unknown. There is an urgent need for gynecologists to undertake a nationwide analysis with correct knowledge and detailed research about family history.

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© 2003 The Japanese Society for Familial Tumors
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