JOURNAL OF FAMILIAL TUMORS
Online ISSN : 2189-6674
Print ISSN : 1346-1052
Decision Making Regarding Therapeutic Options for Multiple Colorectal Cancer in HNPCC
Kohji Tanakaya Hitoshi TakeuchiYoshimasa YasuiAkira TakedaYuzo Umeda
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JOURNAL OPEN ACCESS

2004 Volume 4 Issue 1 Pages 29-32

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Abstract
An excess of multiple colorectal cancers has been reported in hereditary non-polyposis colorectal cancer (HNPCC). The management of patients with colorectal cancer(CRC)should include segmental colectomy in cases of sporadic CRC, and prophylactic subtotal colectomy. The patients need to know that an alternative to subtotal colectomy is segmental colectomy followed by lifelong colonoscopic surveillance. The decision to choose the therapeutic option is made in consideration of the following conditions: method of diagnosis, affection of cancer, site of CRC, age at the onset of CRC, tolerance to operation, and anal sphincter function. In cases of families with a history suggestive of HNPCC but in which the Amsterdam criteria have not been fulfilled, decision making is often difficult. Extended hemicolectomy is a procedure in which half the length of the colon is resected. We propose that extended hemicolectomy should be included as one of the therapeutic options for HNPCC.
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© 2004 The Japanese Society for Familial Tumors
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