A BRCA2 Related Familial Breast Cancer Family in Which Presymptomatic Gene Testing Was Performed in The Family Members Including Twins

Abstract

We performed presymptomatic BRCA gene testing to the three family members including of twins in a familial breast cancer family diagnosed pathogenetic mutation in BRCA2 gene. All members were over the twenty years. We explained familial breast cancer and BRCA gene testing and got autonomic consent before gene testing. Two women were carriers and one was not, and dizygotic twins were made clear by genetically. We told high risk for breast cancer and diet or breast cancer screening for breast cancer prevention to carriers and the same risk of breast cancer as general population to non-carrier in familial tumor counseling.