Ronen Shika Igaku
Online ISSN : 1884-7323
Print ISSN : 0914-3866
ISSN-L : 0914-3866
Original Articles
In Vitro Efficacy of Electrolyzed Dilute Sodium Hypochlorite Solution on Candidal Biofilm
Toshiya KashiwabaraTakeyoshi YoneyamaAtsuko NakamichiTsuyoshi HondaSachie TokoTakaharu GotoKan NagaoTetsuo Ichikawa
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2014 Volume 28 Issue 3 Pages 277-283

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Abstract

The effectiveness of oral care interventions for preventing aspiration pneumonia and barriers to compromised elderly is universally-recognized in present medical practice. Quick and effective methods and materials are needed for oral health care. An electrolyzed dilute sodium hypochlorite solution was chosen as a sterilizing solution for oral health care and the sterilizing effect was evaluated using an in vitro candida biofilm. Three electrolyzed functional waters, namely strongly alkaline water, weakly acidic water, dilute sodium hypochlorite solution, two kinds of commercial mouth wash and distilled water were used as test solutions. Antibiofilm efficacy and residual chlorine concentration were evaluated before/after immersing candidal biofilm specimens in each solution. pH changes of the solutions and macroscopic observations of metal surface were evaluated before/after immersing three kinds of dental metals: steel bar, cobalt-chromium alloy and gold-silver-palladium alloy in the solutions to test the corrosion behavior. An electrolyzed dilute sodium hypochlorite solution showed high bactericidal capability of candida biofilm on cell desks and stable concentration of available chlorine, but high induction of metal corrosion.

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© 2014 Japanese Society of Gerodontology
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