Comparison of clinicopathological findings of early gastric cancer detected with ultrathin transnasal endoscopy and those detected with peroral endoscopy

Abstract

We compared the clinicopathological findings of 310 early gastric cancer cases detected by peroral endoscopy with 72 cases detected by transnasal endoscopy at Kawasaki Medical School and other cooperating hospitals.
We focused on whether there were any differences in the following:(1) Macroscopic types,(2) Size, (3) Three portions of the stomach, (4) Four equal parts of the gastric circumference, (5) Depth of tumor invasion,(6) Histological typing, (7) Stage grouping, (8) Ulcerative findings, and (9) Guideline criteria for endoscopic resection.
Regarding the macroscopic types, IIc lesions accounted for 63.2% by peroral endoscopy and accounted for 61.1% by nasal endoscopy. The mean size was 20.6mm by peroral endoscopy and 19.7mm by nasal endoscopy. The ratio of lesions 10mm or less accounted for 28.4% by peroral endoscopy and 37.5% by nasal endoscopy. The ratio of guideline criteria for lesions in endoscopic resection was 44.2% by peroral endoscopy and 45.8% by nasal endoscopy. We also added the same examination for lesions of 10mm or less. Because there were no significant differences found in both examinations, it is considered that transnasal endoscopy should be recommended for the screening of gastric cancer.