Abstract
Of 6,377 patients who underwent upper gastrointestinal tract endoscopy as part of a complete medical check-up during a 4-year period, we identified duodenal follicular lymphoma in 2 patients. Patient 1 was a 52-year-old woman. Upper gastrointestinal tract endoscopy showed fold thickening in the descending part of the duodenum. Furthermore, there were white plaques and white granular prominences on part of the surface. Patient 2 was a 65-year-old woman. Endoscopy showed white plaques and white granular prominences from the inferior duodenal angulus to the horizontal area. Both patients were diagnosed by biopsy as having grade 1 follicular lymphoma. Although past endoscopic images had visualized part of the lesion in both patients, the physician in charge overlooked the white plaques and white granular prominences without recognizing any abnormalities. In order to identify duodenal follicular lymphomas, it is important to carefully observe between the folds of the duodenum and ensure that characteristic white plaques and white granular prominences are not overlooked.