2015 Volume 53 Issue 2 Pages 212-216
We investigated whether it would be possible to apply the degree of gastric mucosal atrophy determined by endoscopy in multicenter endoscopy examination to the high-risk classification of gastric cancer. Subjects were 40,011 cases examined from 2008 to 2011. The subjects were classified by endoscopic specialists.
Cases classified as C-0, C-1, C-2, C-3, O-1, O-2, and O-3 (Takemoto-Kimura classification) were examined in terms of the sex ratio, the average age, and the cancer discovery rate. The group of cases classified as C-0 and cases classified as C-1 was designated as Group A, and the group of cases classified as C-2 or more advanced was designated as Group B for investigation. As a result, the age odds ratio was 1.039 (P<0.048), the male-to-female odds ratio was 3.146 (P<0.0001), and the Group-B-to-Group-A odds ratio was 4.495 (P<0.0001). In Group B with the degree of gastric mucosal atrophy higher than that of Group A, the cancer discovery rate was significantly higher than that of Group A regardless of the age and sex. At present, the Kanazawa City Office notifies those classified as C2 or more advanced as a result of endoscopy examination that they have a high risk of gastric cancer. In conclusion, we consider that classification of the degree of gastric mucosal atrophy by endoscopy examination is useful for the high-risk classification of gastric cancer in multicenter endoscopy examination.
