Abstract
Since 1999, Ota City has conducted individualized screening where the patient selects endoscopy or direct radiographic imaging as the screening modality. From 2008 to 2013, we performed ABC classification using Helicobacter pylori antibody and the serum pepsinogen method and found that the detection rate of stomach cancer was 0.53% (397/74,352 patients) and that in Group A was 0.19% (62/32,352); Group B, 0.51% (102/19,945); Group C, 1.03% (187/18,148); Group D, 1.17% (46/3,934). The discovery rates using H. pylori antibody and the serum pepsinogen method were 0.76% (289/38,093) and 1.06% (233/22,082), respectively. However, the incidence of cases missed with the H. pylori antibody and serum pepsinogen screening methods were 27.2% (108/397) and 41.3% (164/397), respectively, indicating that using H. pylori antibody fewer cases were overlooked; this method is thus suitable for screening. The H. pylori antibody level of a patient was measured during a medical checkup, and H. pylori screening was conducted to recommend endoscopic examination for antibody-positive patients. Screening of the subjects using only the ABC classification is thought to have a high risk of missed cases. Thus, an efficient endoscopic examination for H. pylori associated gastritis is necessary.
