2022 Volume 60 Issue 1 Pages 3-13
In medical research, statistical methods have been widely utilized. With enhanced expectations for real-world data, highly sophisticated statistical methods have recently been successfully introduced in practice. However, inappropriate application of statistical methods may be observed. Therefore, statistical thinking and reasoning should be appropriately shared among clinical researchers. In this study, we provide an introductory explanation of the statistics. In contrast to a recent randomized clinical trial and a recent observational study evaluating the effectiveness of endoscopies, fundamental ideas behind statistical methods are widely used in clinical research. This is the first part in a series of two successive lectures.