Clinical and pathological characteristics of colorectal cancer detected by colorectal cancer screening in women and elderly people in Iwate Prefecture.

Abstract

Objective: This study aimed to confirm the clinical and pathological characteristics of colorectal cancer cases detected by screening in Iwate Prefecture and verify their significance.

Subjects and methods: Among 1,900 colorectal cancer cases with complete records that were diagnosed based on colonoscopy (TCS) between 2011 and 2020 at this and related facilities, we investigated the number and population of early and advanced cancers regarding the following three factors: i) three background factors: medical history, gender, and age; ii) three characteristics of cancer: tumor site, diameter, and depth (early-stage cancers only). Furthermore, the number and proportion of early-stage cancers type 0-I and 0-II were investigated for the above-mentioned items.

Results: 1) The total number of cancers was the highest in both men and women aged 70 to 74 years (272 and 159 cases, respectively). 2) Advanced cancers showed statistically significant differences in all items of first time, female, elderly, right-sided colon, and tumor diameter of 21 mm or more. 3) The proportion of type 0-II showed statistically significant differences in items of elderly, right-sided colon, tumor diameter of 11 mm or more, and submucosal.

Conclusion: It is important to actively include women and elderly people aged 70 to 74 years as targets recommended for colorectal cancer screening.