A case of accidental coexistence of atypical placental site nodule of the uterine body with ovarian cancer

Abstract

Atypical placental site nodule (APSN) develops from the trophoblast, and is considered as a precursor to epithelioid trophoblastic tumor (ETT). We report a case of accidental coexisting APSN and ovarian cancer. A tumor was discovered in the pelvis of a woman who complained of lower abdominal pain. On the basis of imaging and cytology findings, an ovarian tumor was suspected. However, an endometrial biopsy revealed other atypical cells that had multiple distinct nuclei with eosinophilic or clear cytoplasm and proliferated in an alveolar or fascicular pattern.