2023 Volume 41 Issue 1 Pages 10-18
Objective: To evaluate the usefulness of geriatric assessment (GA) for elderly gynecological cancer patients. Subjects/methods: The subjects were 148 gynecological cancer patients aged 65 years or older who were scheduled for cancer treatment between July 2020 and June 2021 at the Hokkaido Cancer Center and who gave consent for this study. Before treatment, GA was performed using two tools, Geriatric8 (G8) and mini-COG, and scores were calculated. The primary endpoint was the number of cycles of chemotherapy administered without reducing the standard dose, and the relationship between this and the score was examined. The GA was also performed on subjects who had undergone surgery or radiotherapy, and the characteristics of these patients were also examined. Results］ The G8 scores were 17-14.5 in 62 subjects (41.9%), 11-14 in 59 subjects (39.9%), and 3-10 in 27 subjects (18.3%). The most common mini-COG score was 5 (55.4%), but 23 (15.5%) of the patients had a score of 2 or less, which is considered suspicious for dementia. With regard to the primary endpoint, the success rate of G8 was significantly higher (77.5%, 59.5%, and 25.0%), in descending order from the group with the highest score to the group with the lowest score. The lower score group had a significantly lower success rate than the higher or intermediate group (P＝0.002, P＝0.038). On the other hand, there was no significant difference in the success rate for mini-COG scores. Conclusion: The results suggest that the GA is useful as an indicator of the degree of completion of pharmacotherapy for elderly patients with gynecological cancer.
