Japanese Journal of Gynecological Oncology
Online ISSN : 2436-8156
Print ISSN : 1347-8559
A case of BRCA2 pathological variant-positive carcinosarcoma treated with olaparib
Jun KatoSakiko MasumotoKayo NarinobouHiroto KobayashiYoshiaki HoriMasaaki Tanaka
Author information
JOURNAL FREE ACCESS

2023 Volume 42 Issue 3 Pages 272-277

Details
Abstract

Synopsis: Carcinosarcoma is a rare malignant tumor comprising both carcinoma and sarcoma components. We describe a case in which serous tubal intraepithelial carcinoma (STIC) occurred along with omental carcinosarcoma. We ascertained that the STIC had become the primary lesion and metastasized to the omentum. The patient was a carrier of the BRCA2 pathological variant. After adjuvant chemotherapy with docetaxel and carboplatin, maintenance therapy with olaparib was administered. The patient has continued with the maintenance therapy with olaparib for 24 months, and has not had a recurrence. Olaparib may be effective in the treatment of BRCA pathological variant-positive carcinosarcoma.

Content from these authors
© 2023 Japan Society of Gynecologic Oncology
Previous article Next article
feedback
Top