A case of retroperitoneal leiomyosarcoma in a young woman

Abstract

Synopsis: A 23-year-old nulliparous woman was referred to our hospital with a complaint of right lower abdominal pain that had persisted for 3 weeks. Ultrasonography and MRI revealed a mass lesion exceeding 15 cm in diameter, occupying the lower abdomen, with cystic components. Contrast-enhanced CT of the entire body showed no evidence of distant metastasis. Suspecting a malignant ovarian tumor, we performed exploratory laparotomy, which revealed a retroperitoneal tumor originating from the right side of the posterior uterus, with no continuity to the uterus or ovaries. Due to the tumor's location, simultaneous removal of the retroperitoneal tumor and the right adnexa was necessary. The abdomen was closed with preservation of the uterus and left adnexa. Histopathological examination confirmed the tumor as a retroperitoneal leiomyosarcoma. After thorough discussion with the patient and her family, the decision was made to proceed with additional treatment. The patient is currently under observation following six courses of single-agent doxorubicin therapy as adjuvant chemotherapy.Key words: retroperitoneal, leiomyosarcoma